南开2019年代表性论文

NKU

医学院王悦冰副教授，生命科学学院丁丹研究员，李宗金教授合作ACS Nano，通讯作者：王悦冰，丁丹，李宗金
ACS Nano, Just Accepted Publication Date (Web): March 7, 2019 (Article) DOI: 10.1021/acsnano.8b09776
https://pubs.acs.org/doi/abs/10.1021/acsnano.8b09776

In Vivo Real-Time Imaging of Extracellular Vesicles in Liver Regeneration via Aggregation-Induced Emission Luminogens
Hongmei Cao, †, ∞ Zhiwei Yue, †, ∞ Heqi Gao, ‡ Chao Chen, ‡ Kaige Cui, † Kaiyue Zhang,† Yuanqiu Cheng, † Guoqiang Shao, § Deling Kong, ‡ Zongjin Li, *, † Dan Ding,

*, ‡ Yuebing Wang, *, †
† Nankai University School of Medicine, Tianjin 300071, China
‡ The Key Laboratory of Bioactive Materials, Ministry of Education, Nankai University, The College of Life Science, Tianjin 300071, China
§ Department of Nuclear Medicine, Nanjing First Hospital, Nanjing Medical University, Nanjing 210006, China
∞ H.M.C. and Z.W.Y. contributed equally to this work.
Corresponding Authors:
*E-mail: wangyuebing@nankai.edu.cn (Yuebing Wang)
*E-mail: dingd@nankai.edu.cn (Dan Ding)
*E-mail: zongjinli@nankai.edu.cn (Zongjin Li)

NKU

药学院和药物化学生物学国家重点实验室刘遵峰教授Advanced Functional Materials，通讯作者：刘遵峰
Advanced Functional Materials Early View First published: 07 March 2019 10.1002/adfm.201808241
https://onlinelibrary.wiley.com/doi/10.1002/adfm.201808241

Moisture Sensitive Smart Yarns and Textiles from Self-Balanced Silk Fiber Muscles
Tianjiao Jia, Yang Wang, Yuanyuan Dou, Yaowang Li, Monica Jung de Andrade, Run Wang, Shaoli Fang, Jingjing Li, Zhou Yu, Rui Qiao, Zhuangjian Liu, Yuan Cheng, Yewang Su, Majid Minary-Jolandan, Ray H. Baughman, Dong Qian, and Zunfeng Liu*
T. Jia, Y. Dou, J. Li, Prof. Z. Liu
State Key Laboratory of Medicinal Chemical Biology, Key Laboratory of Functional Polymer Materials, College of Pharmacy, Nankai University, Tianjin 300071, China
E-mail: liuzunfeng@nankai.edu.cn
Y. Wang, Prof. D. Qian, Prof. M. Minary-Jolandan
Department of Mechanical Engineering, University of Texas at Dallas, Richardson, TX 75080, USA
Dr. Y. Li
School of Life Sciences, Tsinghua University, Beijing 100084, China
Dr. M. Jung de Andrade, Dr. S. Fang, Prof. R. H. Baughman
Alan G. MacDiarmid NanoTech Institute, University of Texas at Dallas, Richardson, TX 75080, USA
R. Wang
College of Electronic Information and Optics Engineering, Nankai University, Tianjin 300071, China
Z. Yu, Prof. R. Qiao
Center for Soft Matter and Biological Physics, Virginia Tech, Blacksburg, VA 24061, USA
Prof. Z. Liu, Prof. Y. Cheng
Institute of High Performance Computing, Agency for Science Technology and Research (A*STAR), Singapore 138632, Singapore
Prof. Y. Su
State Key Laboratory of Nonlinear Mechanics, Institute of Mechanics, Chinese Academy of Sciences, Beijing 100190, China
Prof. Y. Su
School of Engineering Science, University of Chinese Academy of Sciences, Beijing 100049, China
Prof. Y. Su
Beijing Key Laboratory of Engineered Construction and Mechanobiology, Institute of Mechanics, Chinese Academy of Sciences, Beijing 100190, China

NKU

元素有机化学研究所梁广鑫教授Angewandte Chemie International Edition，通讯作者：梁广鑫
Angewandte Chemie International Edition Accepted Articles First published: 05 March 2019 10.1002/anie.201902043
https://onlinelibrary.wiley.com/doi/10.1002/anie.201902043

Total synthesis of (−)-Indoxamycins A and B
Naifeng Hu, Changming Dong, Cuifang Zhang, Guangxin Liang*
State Key Laboratory of Elemento-organic Chemistry, College of Chemistry, Nankai University, Tianjin 300071 (China)
E-mail: lianggx@nankai.edu.cn

NKU

化学学院袁直教授Nano Lett.，通讯作者：袁直
Nano Lett., Just Accepted Publication Date (Web): February 25, 2019 (Communication) DOI: 10.1021/acs.nanolett.8b04645
https://pubs.acs.org/doi/abs/10.1021/acs.nanolett.8b04645

Reversible shielding between dual ligands for enhanced tumor accumulation of ZnPc-loaded micelles
Jing Cao,† Xuefeng Gao,† Mingbo Cheng,† Xiaoyan Niu,† Xiaomin Li,† Yapei Zhang,† Yang Liu,† Wei Wang,† Zhi Yuan*,†,‡
†Key Laboratory of Functional Polymer Materials of the Ministry of Education, Institute of Polymer Chemistry, College of Chemistry, Nankai University, Tianjin 300071, China
‡Collaborative Innovation Center of Chemical Science and Engineering (Tianjin), Tianjin 300071, China
Corresponding Author
*Email: zhiy@nankai.edu.cn.

NKU

材料科学与工程学院梁嘉杰课题组Advanced Energy Materials，通讯作者：梁嘉杰
Advanced Energy Materials Early View First published: 25 February 2019 10.1002/aenm.201803987
https://onlinelibrary.wiley.com/doi/10.1002/aenm.201803987

Hydrous RuO2-Decorated MXene Coordinating with Silver Nanowire Inks Enabling Fully Printed Micro-Supercapacitors with Extraordinary Volumetric Performance
Hongpeng Li, Xiran Li, Jiajie Liang,* and Yongsheng Chen
H. Li, X. Li, Prof. J. Liang, Prof. Y. Chen
School of Materials Science and Engineering, National Institute for Advanced Materials, Nankai University, Tianjin 300350, P. R. China
E-mail: liang0909@nankai.edu.cn
Prof. J. Liang, Prof. Y. Chen
Key Laboratory of Functional Polymer Materials of Ministry of Education, College of Chemistry, Nankai University, Tianjin 300350, P. R. China
Prof. J. Liang
Tianjin Key Laboratory of Metal and Molecule-Based Material Chemistry, and Collaborative Innovation Center of Chemical Science and Engineering (Tianjin), Nankai University, Tianjin 300350, P. R. China

NKU

物理科学学院陈树琪教授，程化副教授Phys. Rev. Lett.，通讯作者：程化，陈树琪
Phys. Rev. Lett. Accepted 25 February 2019
https://journals.aps.org/prl/acc ... f750dfb74efe229a951
http://chenlab.nankai.edu.cn/My%20published%20paper/prl2019.pdf

Experimental realization of Type-II Weyl points and Fermi arcs in phononic crystal
Boyang Xie1, Hui Liu1, Hua Cheng1;3, Zhengyou Liu2, Shuqi Chen1;3;4,y and Jianguo Tian1;3;4
1 The Key Laboratory of Weak Light Nonlinear Photonics, Ministry of Education, School of Physics and TEDA Institute of Applied Physics, Nankai University, Tianjin 300071, China
2 Key Laboratory of Arti cial Micro- and Nanostructures of Ministry of Education and School of Physics and Technology, Wuhan University, Wuhan 430072, China
3 The collaborative Innovation Center of Extreme Optics, Shanxi University, Taiyuan, Shanxi 030006, China and
4 Renewable Energy Conversion and Storage Center, Nankai University, Tianjin 300071, China
 hcheng@nankai.edu.cn
y schen@nankai.edu.cn

NKU

化学学院李福军研究员Advanced Energy Materials，通讯作者：李福军
Advanced Energy Materials Early View First published: 27 February 2019 10.1002/aenm.201900022
https://onlinelibrary.wiley.com/doi/10.1002/aenm.201900022

A High-Power Na3V2(PO4)3-Bi Sodium-Ion Full Battery in a Wide Temperature Range
Chenchen Wang, Dongfeng Du, Mingming Song, Yunhai Wang, and Fujun Li*
C. Wang, D. Du, M. Song, Prof. F. Li
Key Laboratory of Advanced Energy Materials Chemistry, (Ministry of Education), College of Chemistry, Nankai University, Tianjin 300071, P. R. China
E-mail: fujunli@nankai.edu.cn
Prof. Y. Wang
Department of Environmental Science and Engineering, Xi’an Jiaotong University, Xi’an 710049, P. R. China

NKU

化学学院焦丽芳教授Advanced Materials，通讯作者：焦丽芳
Advanced Materials Early View First published: 27 February 2019 10.1002/adma.201806304
https://onlinelibrary.wiley.com/doi/10.1002/adma.201806304

Binder-Free Electrodes for Advanced Sodium-Ion Batteries
Ting Jin, Qingqing Han, and Lifang Jiao*
Dedicated to the 100th anniversary of Nankai University

Dr. T. Jin, Q. Han, Prof. L. Jiao
Key Laboratory of Advanced Energy Materials Chemistry (Ministry of Education), Renewable Energy Conversion and Storage Center, College of Chemistry, Nankai University, Tianjin 300071, China
E-mail: jiaolf@nankai.edu.cn

NKU

元素有机化学研究所朱守非教授J. Am. Chem. Soc.，通讯作者：朱守非
J. Am. Chem. Soc., Just Accepted Publication Date (Web): February 27, 2019 (Communication) DOI: 10.1021/jacs.9b02127
https://pubs.acs.org/doi/abs/10.1021/jacs.9b02127

Iron-Catalyzed Dihydrosilylation of Alkynes: Efficient Access to Geminal Bis(silanes)
Meng-Yang Hu,1 Jie Lian,1 Wei Sun,1 Tian-Zhang Qiao,1 and Shou-Fei Zhu*,1
1 State Key Laboratory and Institute of Elemento-Organic Chemistry, College of Chemistry, Nankai University, Tianjin 300071, China
Corresponding Author
* sfzhu@nankai.edu.cn

NKU

材料科学与工程学院周震教授共同通讯Advanced Functional Materials，通讯作者：Dianzeng Jia，周震
Advanced Functional Materials Early View First published: 27 February 2019 10.1002/adfm.201807895
https://onlinelibrary.wiley.com/doi/10.1002/adfm.201807895
南开共同通讯&并列一作

LiFePO4 Particles Embedded in Fast Bifunctional Conductor rGO&C@Li3V2(PO4)3 Nanosheets as Cathodes for High-Performance Li-Ion Hybrid Capacitors
Yue Zhang, Zihe Zhang, Yakun Tang, Dianzeng Jia,* Yudai Huang, Weikong Pang, Zaiping Guo, and Zhen Zhou*
Y. Zhang, Dr. Y. K. Tang, Prof. D. Z. Jia, Prof. Y. D. Huang
Key Laboratory of Energy Materials Chemistry, Ministry of Education, Institute of Applied Chemistry, Xinjiang University, Urumqi 830046, Xinjiang, China
E-mail: jdz@xju.edu.cn
Z. Zhang, Prof. Z. Zhou
School of Materials Science and Engineering, Institute of New Energy Material Chemistry, Renewable Energy Conversion and Storage Center (ReCast), Key Laboratory of Advanced Energy Materials Chemistry (Ministry of Education), Nankai University, Tianjin 300350, China
E-mail: zhouzhen@nankai.edu.cn
Dr. W. K. Pang, Prof. Z. P. Guo
Institute for Superconducting and Electronic Materials, University of Wollongong, NSW 2522, Australia
Prof. Z. Zhou
School of Chemical Engineering and Energy, Zhengzhou University, Zhengzhou 450001, China
Y.Z. and Z.H.Z. contributed equally to this work.

NKU

药物化学生物学国家重点实验室陈佺课题组NAT COMMUN，通讯作者：马彪（博士后）、朱玉山、陈佺
Nature Communications, volume 10, Article number: 1034 (2019)，DOI:10.1038/s41467-019-08618-y，Published: 04 March 2019
https://www.nature.com/articles/s41467-019-08618-y

The SIAH2-NRF1 axis spatially regulates tumor microenvironment remodeling for tumor progression
Biao Ma1, Hongcheng Cheng1, Chenglong Mu1, Guangfeng Geng1, Tian Zhao1, Qian Luo1, Kaili Ma1，Rui Chang1, Qiangqiang Liu1, Ruize Gao1, Junli Nie1, Jiaying Xie1, Jinxue Han1, Linbo Chen1, Gui Ma1, Yushan Zhu1 & Quan Chen1,2

1 State Key Laboratory of Medicinal Chemical Biology, Tianjin Key Laboratory of Protein Sciences, College of Life Sciences, Nankai University, Tianjin 300071, China.
2 State Key Laboratory of Membrane Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China. These authors contributed equally: Biao Ma, Hongcheng Cheng. These authors jointly supervised this work: Biao Ma, Yushan Zhu, Quan Chen. Correspondence and requests for materials should be addressed to B.M. (email: biaoma@mail.nankai.edu.cn) or to Y.Z. (email: zhuys@nankai.edu.cn) or to Q.C. (email: chenq@ioz.ac.cn)

Abstract


The interactions between tumor cells with their microenvironments, including hypoxia, acidosis and immune cells, lead to the tumor heterogeneity which promotes tumor progression. Here, we show that SIAH2-NRF1 axis remodels tumor microenvironment through regulating tumor mitochondrial function, tumor-associated macrophages (TAMs) polarization and cell death for tumor maintenance and progression. Mechanistically, low mitochondrial gene expression in breast cancers is associated with a poor clinical outcome. The hypoxia-activated E3 ligase SIAH2 spatially downregulates nuclear-encoded mitochondrial gene expression including pyruvate dehydrogenase beta via degrading NRF1 (Nuclear Respiratory Factor 1) through ubiquitination on lysine 230, resulting in enhanced Warburg effect, metabolic reprogramming and pro-tumor immune response. Dampening NRF1 degradation under hypoxia not only impairs the polarization of TAMs, but also promotes tumor cells to become more susceptible to apoptosis in a FADD-dependent fashion, resulting in secondary necrosis due to the impairment of efferocytosis. These data represent that inhibition of NRF1 degradation is a potential therapeutic strategy against cancer.

NKU

南开大学化学学院程鹏课题组赵斌教授ANGEWANDTE，通讯作者：Han-Shi Hu，Nikolas Kaltsoyannis，赵斌
Angewandte Chemie International Edition，DOI:10.1002/anie.201901786,First published: 21 February 2019
https://www.onlinelibrary.wiley.com/doi/10.1002/anie.201901786

High Uptake of ReO4− by a Radiation Resistant [Th48Ni6] Nanocage-Based Metal−Organic Framework
Hang Xu,[a] Chun-Shuai Cao,[a] Han-Shi Hu,*[b,c] Shi-Bin Wang,[b Jin-Cheng Liu,[b Peng Cheng,[a]Nikolas Kaltsoyannis,*[c] Jun Li,b] Bin Zhao*[a]

a] Dr. H. Xu, Dr. C.-S. Cao, Prof. Dr. P. Cheng, Prof. Dr. B. Zhao
Department of Chemistry，Key Laboratory of Advanced Energy Material Chemistry, Nankai University, Tianjin, 300071, China
E-mail: zhaobin@nankai.edu.cn
b]Prof. Dr. H.-S. Hu, Dr. W.-S. Bin, Mr. J. C. Liu, Prof. Dr. J. Li
Department of Chemistry and Key Laboratory of Organic Optoelectronics & Molecular Engineering of Ministry of Education, Tsinghua University，Beijing 100084, China
E-mail: hshu@mail.tsinghua.edu.cn
c] Prof. Dr. H.-S. Hu, Prof. Dr. N. Kaltsoyannis
School of Chemistry, The University of Manchester, Oxford Road, Manchester, M13 9PL, UK
E-mail: nikolas.kaltsoyannis@manchester.ac.uk

NKU

生命科学学院杨志谋课题组Nano Lett.，通讯作者：王恺，高洁，杨志谋
Nano Lett., Just Accepted Publication Date (Web): February 21, 2019 (Communication) DOI: 10.1021/acs.nanolett.8b04406
https://pubs.acs.org/doi/abs/10.1021/acs.nanolett.8b04406

Supramolecular Nanofibers with Superior Bioactivity to IGF-1
Yuna Shang,†,♯ Dengke Zhi,†,♯ Guowei Feng,‡ Zhongyan Wang,† Duo Mao,§ Shuang Guo,† Ruihua Liu,† Lulu Liu,† Shuhao Zhang,† Shenghuan Sun,† Kai Wang,*,†, Deling Kong,† Jie Gao*,† & Zhimou Yang*,†,∮
†Key Laboratory of Bioactive Materials, Ministry of Education, College of Life Sciences, State Key Laboratory of Medicinal Chemical Biology, Collaborative Innovation Center of Chemical Science and Engineering, and National Institute of Functional Materials, Nankai University, Tianjin 300071, P. R. China
‡Department of Genitourinary Oncology, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Tianjin Key Laboratory of Cancer Prevention and Therapy, Tianjin's Clinical Research Center for Cancer, Tianjin 300060, P. R. China
§Department of Chemical and Biomolecular Engineering, National University of Singapore, Engineering Drive 4, Singapore, 117585
∮Jiangsu Center for the Collaboration and Innovation of Cancer Biotherapy, Cancer Institute, Xuzhou Medical University, Xuzhou, Jiangsu, P. R. China
*Corresponding Authors: yangzm@nankai.edu.cn (phone: +86 22 23502875);
chemgaojie@nankai.edu.cn; wangkai@nankai.edu.cn

NKU

材料科学与工程学院卜显和课题组Coordination Chemistry Reviews，通讯作者：胡同亮，卜显和
Coordination Chemistry Reviews, Volume 387, 15 May 2019, Pages 79-120
https://www.sciencedirect.com/sc ... i/S001085451830599X

Metal-organic framework-based heterogeneous catalysts for the conversion of C1 chemistry: CO, CO2 and CH4
Wen-Gang Cui a, Guo-Ying Zhang b, Tong-Liang Hu ac*, Xian-He Bu ad*
a School of Materials Science and Engineering, Tianjin Key Laboratory of Metal and Molecule-Based Material Chemistry, National Institute for Advanced Materials, Nankai University, Tianjin 300350, China
b Tianjin Key Laboratory of Structure and Performance for Functional Molecules, Key Laboratory of Inorganic-Organic Hybrid Functional Material Chemistry (Ministry of Education), College of Chemistry, Tianjin Normal University, Tianjin 300387, China
c Tianjin Key Lab for Rare Earth Materials and Applications, Nankai University, Tianjin 300350, China
d State Key Laboratory of Elemento-Organic Chemistry, Nankai University, Tianjin 300071, China
* Corresponding authors.
tlhu@nankai.edu.cn
buxh@nankai.edu.cn

NKU

化学学院程鹏课题组Advanced Materials，通讯作者：师唯，程鹏
Advanced Materials Early View First published: 21 February 2019 10.1002/adma.201805871
https://onlinelibrary.wiley.com/doi/10.1002/adma.201805871

Multicenter Metal–Organic Framework-Based Ratiometric Fluorescent Sensors
Shuangyan Wu, Hui Min, Wei Shi,* and Peng Cheng* DOI: 10.1002/adma.201805871
Dr. S. Wu, H. Min, Prof. W. Shi, Prof. P. Cheng
Key Laboratory of Advanced Energy Materials Chemistry (MOE), College of Chemistry, Nankai University, Tianjin 300071, China
E-mail: shiwei@nankai.edu.cn; pcheng@nankai.edu.cn
Prof. P. Cheng
State Key Laboratory of Elemento-Organic Chemistry, Nankai University, Tianjin 300071, China

NKU

南开大学材料科学与工程学院卜显和课题组Angewandte Chemie International Edition，通讯作者：卜显和、许健
Angewandte Chemie International Edition Accepted Articles First published: 19 February 2019 10.1002/anie.201900190
https://onlinelibrary.wiley.com/doi/10.1002/anie.201900190


A Dual-Stimuli-Responsive Coordination Network Featuring a Reversible Wide-Range Luminescence Tuning Behavior
Zhao-Quan Yao, Jian Xu,* Bo Zou, Zhenpeng Hu, Kai Wang, Yi-Jia Yuan, Ya-Ping Chen, Rui Feng, Jian-Bo Xiong, Jialei Hao, and Xian-He Bu*
Dr. Z.-Q. Yao, Y.-J. Yuan, R. Feng, J.-B. Xiong, Prof. X.-H. Bu
State Key Laboratory of Elemento-Organic Chemistry, College of Chemistry, Nankai University, Tianjin 300071, China.
E-mail: buxh@nankai.edu.cn
Dr. Z.-Q. Yao, Dr. J. Xu, R. Feng, J.-B. Xiong, Prof. X.-H. Bu
School of Materials Science and Engineering, National Institute for Advanced Materials, TKL of Metal and Molecule-Based Material Chemistry, Nankai University, Tianjin 300350, China.
E-mail: jxu@nankai.edu.cn
Prof. B. Zou, Dr. K. Wang, Y.-P. Chen
State Key Laboratory of Superhard Materials, Jilin University, Changchun 130012, China.
Prof. Z. Hu, J. Hao
School of Physics, Nankai University, Tianjin 300071, China.
Prof. X.-H. Bu
Collaborative Innovation Center of Chemical Science and Engineering (Tianjin), Tianjin 300072, China.

Abstract
We herein report a new coordination network that deforms in a smooth and reversible manner under either thermal or pressure stimulation. Concomitantly, the organic fluorophores coordinatively bound to the channel in a face‐to‐face arrangement respond to this structural deformation by finely adapting their conformation and arrangement. As a result, the material exhibits a remarkable dual‐stimuli‐responsive luminescence shift across almost the entire visible region: The emission color of the crystal gradually changes from cyan to green by heating and then to red by pressure compression. Furthermore, each stage exhibits a linear dependence of both the emission maximum and intensity on stimulus and is fully

NKU

今年百年校庆，南开可能在Adv. Mater.上发表special issue？目前已知发表三篇review一篇progress report，不过都是invited。
刘育（有机/物化），陈永胜（高分子/纳米），卜显和（无机），陈树琪（物理），按道理学校不太鼓励发review的，毕竟不是原创性成果，突然这么密集发表，有点奇怪。
http://mse.nankai.edu.cn/xjl/list.htm

NKU

南开大学化学学院陈永胜课题组Advanced Materials，通讯作者：陈永胜
Advanced Materials Early View First published: 18 February 2019 10.1002/adma.201805843
https://onlinelibrary.wiley.com/doi/10.1002/adma.201805843


Integrated Perovskite/Bulk-Heterojunction Organic Solar Cells
Yongsheng Liu and Yongsheng Chen*
Prof. Y. Liu, Prof. Y. Chen
The Centre of Nanoscale Science and Technology and Key Laboratory of Functional Polymer Materials, Institute of Polymer Chemistry, College of Chemistry, Nankai University, Tianjin 300071, China
E-mail: yschen99@nankai.edu.cn

Abstract
The recently emerged integrated perovskite/bulk‐heterojunction (BHJ) organic solar cells (IPOSCs) without any recombination layers have generated wide attention. This type of device structure can take the advantages of tandem cells using both perovskite solar and near‐infrared (NIR) BHJ organic solar materials for wide‐range sunlight absorption and the simple fabrication of single junction cells, as the low bandgap BHJ layer can provide additional light harvesting in the NIR region and the high open‐circuit voltage can be maintained at the same time. This progress report highlights the recent developments in such IPOSCs and the possible challenges ahead. In addition, the recent development of perovskite solar cells and NIR organic solar cells is also covered to fully underline the importance and potential of IPOSCs.

NKU

南开大学元素有机化学研究所刘育课题组Advanced Materials，通讯作者：刘育
Advanced Materials Early View First published: 18 February 2019 10.1002/adma.201806158
https://onlinelibrary.wiley.com/doi/10.1002/adma.201806158


Cyclodextrin-Based Multistimuli-Responsive Supramolecular Assemblies and Their Biological Functions
Ying-Ming Zhang, Yao-Hua Liu, and Yu Liu*

Dr. Y.-M. Zhang, Y.-H. Liu, Prof. Y. Liu
College of Chemistry, State Key Laboratory of Elemento-Organic Chemistry, Nankai University, Tianjin 300071, China
E-mail: yuliu@nankai.edu.cn
Prof. Y. Liu
Collaborative Innovation Center of Chemical Science and Engineering (Tianjin), Tianjin 300072, China

Abstract
Cyclodextrins (CDs), which are a class of cyclic oligosaccharides extracted from the enzymatic degradation of starch, are often utilized in molecular recognition and assembly constructs, primarily via host–guest interactions in water. In this review, recent progress in CD‐based supramolecular nanoassemblies that are sensitive to chemical, biological, and physical stimuli is updated and reviewed, and intriguing examples of the biological functions of these nanoassemblies are presented, including pH‐ and redox‐responsive drug and gene delivery, enzyme‐activated specific cargo release, photoswitchable morphological interconversion, microtubular aggregation, and cell–cell communication, as well as a geomagnetism‐controlled nanosystem for the suppression of tumor invasion and metastasis. Moreover, future perspectives and challenges in the fabrication of intelligent CD‐based biofunctional materials are also discussed at the end of this review, which is expected to promote the translational development of these nanomaterials in the biomedical field.

NKU

lygxia 发表于 2019-2-18 13:52
被黑了么？还是啥原因

应该是没有人维护了吧。具体不是很清楚。如果有人维护，论坛应该早就修好了

应该把浙大academic818叫回来繁荣一下NCKU，哈哈